Ketoconazole Retains Activity in Advanced Prostate Cancer Patients with Progression Despite Flutamide Withdrawal

Mutation of the Androgen-Receptor Gene in Metastatic Androgen-Independent Prostate Cancer

Mary‐Ellen Taplin, Glenn J. Bubley, Todd D. Shuster et al. · New England Journal of Medicine · 1995 · 1.3K citations · Full text

Medicine, Genetics, Oncology +17

Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer.

Howard I. Scher, William Kevin Kelly · Journal of Clinical Oncology · 1993 · 413 citations

Medicine, Oncology, Urology +17

Prostate-specific antigen as a measure of disease outcome in metastatic hormone-refractory prostate cancer.

William Kevin Kelly, Howard I. Scher, Madhu Mazumdar et al. · Journal of Clinical Oncology · 1993 · 389 citations

Medicine, Oncology, Urology +13

Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation

Jos Veldscholte, Cor Berrevoets, Albert O. Brinkmann et al. · Biochemistry · 1992 · 282 citations

Life Sciences, Biochemistry, Endocrinology +16

KETOCONAZOLE THERAPY FOR ADVANCED PROSTATE CANCER

John Trachtenberg, Allan Pont · The Lancet · 1984 · 164 citations

Medicine, Oncology, Pharmacology +6