THE N-DEMETHYLATION OF MORPHINE AND CODEINE USING METHYL CHLOROFORMATE

Novel analgesics and molecular rearrangements in the morphine-thebaine group. III. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeine

Kenneth W. Bentley, D. G. Hardy · Journal of the American Chemical Society · 1967 · 143 citations

Medicine, Medicinal Chemistry, Pharmacology +8

2,2,2-trichloroethyl chloroformate: A general reagent for demethylation of tertiary methylamines

Thomas A. Montzka, John D. Matiskella, R. A. Partyka · Tetrahedron Letters · 1974 · 110 citations

Natural Sciences, Chemistry, Organic Chemistry +1

Improved procedure for the N-demethylation of 6,7-benzomorphans, morphine, and codeine

Kenner C. Rice · The Journal of Organic Chemistry · 1975 · 69 citations

Pharmacy, Chemistry, Pharmacology +5

N-Demethylation of morphine and structurally related compounds with chloroformate esters

Mahmoud M. Abdel‐Monem, Philip S. Portoghese · Journal of Medicinal Chemistry · 1972 · 62 citations

Medicine, Chemistry, Pharmacology +6