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Synthetic Studies on Optically Active b-Lactams. Asymmetric Synthesis of b-Lactams by the Cyclocondensation Utilizing Chiral Heterocyclic Compounds Derived from L-(+)-Tartaric Acid and (S)-Glutamic Acid

Nobuo Ikota, Akira Hanaki

Heterocycles · 1984 · 20 citations · 0 references

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Abstract

Asymmetric cyclocondensation of the chiral heterocyclic compounds (2,:) with imines (2) gave either cisor trans-8-lactams with high diastereomeric purity up to 96%, and the