Syntheseversuche in der Emetin‐Reihe. 3. Mitteilung. 2‐Hydroxy‐hydrobenzo[a]chinolizine

Abstract

Abstract The reduction of various 2‐oxo‐1,2,3,4,6,7‐hexahydro‐11b H ‐benzo[a]quinolizines substituted in 3‐position is described. Depending upon the method of reduction and the experimental conditions applied, either a sterically homogeneous carbinol or a mixture of two epimeric carbinols is obtained. Their stereochemistry is discussed. Various derivatives of these alcohols are described.