PEDIATRICS · 1959 · 12 citations · 0 references
MedicineInfectious DiseasesPediatricsInfectious Disease PathologyPediatric Infectious DiseasesPediatric PathologyImmunocompromised Host InfectionsInfant Infectious DiseasesParasitic InfectionsParasitic PathologyPediatric Antimicrobial TherapyPediatric Clinical ImmunologyParasitic Infection TreatmentPediatric Antifungal TherapyPediatric Infection TreatmentTherapeutic Trial Design
Four cases with disseminated histoplasmosis are reported; three were in children under 12 months of age. All responded gratifyingly to amphotericin B therapy given intravenously. The value of Heiner's agar-gel technique for histoplasmin precipitin as a diagnostic tool was substantiated. Further therapeutic trial of amphotericin B in disseminated infantile histoplasmosis seems warranted.