Concepedia

<i>In Vitro</i> and Intracellular Activity of Imipenem Combined with Rifabutin and Avibactam against Mycobacterium abscessus

Eva Le Run, Michel Arthur, Jean‐Luc Mainardi

Antimicrobial Agents and Chemotherapy · 2018 · 35 citations · 23 references

DOIFull text

Open access

Concepts

Abstract

Repurposing drugs may be useful as an add-on in the treatment of Mycobacterium abscessus pulmonary infections, which are particularly difficult to cure. M. abscessus naturally produces a β-lactamase, Bla MAb , which is inhibited by avibactam.

References

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