Recent Developments in the Synthesis of Heterocycles from Enamines and Isothiocyanates

Abstract

A serendipitous synthesis of multifunctional thiophene derivatives i s described.Nitroenamineisothiocyanate adducts have been used t o prepare 3-nitrothiophenes, 4-nitroisotbiazoles, 5-nitropyrimidines and 4-nitropyrazoles.