Plastic & Reconstructive Surgery · 1999 · 202 citations · 11 references
MedicinePlastic SurgerySurgeryAesthetic SurgeryDermatologic SurgeryMicrosurgeryBotulinum Toxin TherapyBotulinum Toxin TreatmentFacial Plastic SurgeryWrinkle ReductionAesthetic Facial SurgeryCrow's Feet TreatmentFillersForehead Lines TreatmentForehead Wrinkle TreatmentGlabellar Lines TreatmentTreatment Of Facial RhytidesWrinkle Correction
Our improved understanding of the pathophysiology of facial lines, wrinkles, and furrows has broadened the treatment options for a variety of facial cosmetic blemishes. The persistence or recurrence of certain facial rhytids after surgery has confirmed the lack of full comprehension of their origin. Glabellar forehead furrows (frown lines) and lateral canthal rhytids (crow's feet) have been the most popular facial lines that have been shown to be mostly the result of regional hyperkinetic muscles, and their eradication may be more suitable, at times, to chemodenervation than to soft-tissue fillers, skin resurfacing, or surgical resection. Aesthetic surgical procedures that have yielded suboptimal results may also occur from failure to recognize other causative factors including hyperkinetic or dynamic musculature, which may contribute to etiology of the visible soft-tissue changes and lack of persistent effect after surgery. Chemodenervation with botulinum toxin A (Botox) has proven to be useful both as a primary treatment for certain facial rhytids and as an adjunctive agent for a variety of facial aesthetic procedures to obtain optimal results. (Plast. Reconstr. Surg. 103: 701, 1999.)
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Richard L. Anderson, Dennis D. Gordy · Archives of Ophthalmology · 1979 · 515 citations
Medicine, Plastic Surgery, Surgery +14
Botulinum toxin for blepharospasm: single-fiber EMG studies
Neurology · 1986 · 175 citations
Medicine, Neurology, Neuroscience +17
Richard P. Clark, Craig E. Berris · Plastic & Reconstructive Surgery · 1989 · 140 citations