Nanoparticulate systems for brain delivery of drugs

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Carlos Cordon‐Cardo, James P. O’Brien, D Casals et al. · Proceedings of the National Academy of Sciences · 1989 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +16

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

Robert E. Pitas, J K Boyles, Susan H. Lee et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1987 · 694 citations

Life Sciences, Biochemistry, Neuroscience +11

Brain drug delivery of small molecules using immunoliposomes

Jörg Huwyler, Dafang Wu, William M. Pardridge · Proceedings of the National Academy of Sciences · 1996 · 650 citations

Pharmacy, Pharmaceutics, Pharmacology +17

A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier

Bénédicte Dehouck, Laurence Fénart, Marie‐Pierre Dehouck et al. · The Journal of Cell Biology · 1997 · 576 citations · Full text

Life Sciences, Biochemistry, Neuroscience +15

An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro

Marie‐Pierre Dehouck, Stéphane Méresse, Pierre Delorme et al. · Journal of Neurochemistry · 1990 · 543 citations

Engineering, Cell Biology, Neuroscience +17