SnAP Reagents for the Transformation of Aldehydes into Substituted Thiomorpholines—An Alternative to Cross‐Coupling with Saturated Heterocycles

Abstract

Die Umwandlung von Aldehyden in N-unsubstituierte 3-Thiomorpholine bildet eine einfache Alternative zu metallkatalysierten Kreuzkupplungen, die zur Funktionalisierung gesättigter N-Heterocyclen im Allgemeinen ungeeignet sind. Eine kupfervermittelte radikalische Cyclisierung ist der Schlüssel für die milden Bedingungen, die hohe Verträglichkeit mit funktionellen Gruppen und den großen Substratbereich, den diese Reagentien bieten. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.