Angewandte Chemie International Edition · 1999 · 16 citations · 0 references
Natural SciencesChemistryCatalysisOrganic ChemistryCatalyst DesignCatalyst SynthesisHeterocycle SynthesisHeterogeneous CatalysisHomogeneous CatalysisOrganic SynthesisHeterocycle FunctionalizationHydrogenation CatalysisHydrogenation ReactionsOrganic SubstratesPalladium CatalystsTransition-metal-catalyzed FunctionalizationTransition-metal-catalyzed Heterocycle Synthesis
Zero-valent palladium precatalysts containing rigid bidentate bis(arylimino)acenaphthene ligands (shown schematically) facilitate the highly stereoselective homogeneous catalytic hydrogenation of alkynes to (Z)-alkenes. Internal, terminal, aryl-substituted, and cyclic alkynes are suitable substrates, as are some enynes, which are chemoselectively hydrogenated to dienes. E=CO2Me; R1, R2=4-OCH3, 4-CH3, 2,6-(CH3)2.