Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies

Proposal for Revised Classification of Epilepsies and Epileptic Syndromes

Epilepsia · 1989 · 5.4K citations

Medicine, Neurology, Neuroscience +12

The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

Claudio Rivera, Juha Voipio, John A. Payne et al. · Nature · 1999 · 2.1K citations

Life Sciences, Neurobiology, Neuroscience +14

X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity

Raimund Dutzler, Ernest B. Campbell, Martine Cadène et al. · Nature · 2002 · 1.6K citations

Natural Sciences, Biochemistry, Chemistry +17

Mutant GABAA receptor γ2-subunit in childhood absence epilepsy and febrile seizures

Robyn H. Wallace, Carla Marini, Steven Petrou et al. · Nature Genetics · 2001 · 782 citations

Medicine, Neurology, Neuroscience +16

First genetic evidence of GABAA receptor dysfunction in epilepsy: a mutation in the γ2-subunit gene

Stéphanie Baulac, Gilles Huberfeld, Isabelle Gourfinkel‐An et al. · Nature Genetics · 2001 · 766 citations

Life Sciences, Genetics, Neuroscience +16