Endocrinology · 1996 · 16 citations · 0 references
Life SciencesEndocrinologyMolecular BiologyCell ProliferationGene ExpressionSteroid BiochemistryAndrogen PhysiologyGrowth Factor SignalingHormonal RegulationHormone Signal TransductionSteroid Hormone SignalingAndrogen Action In ProstateDose-response Curve AnalysisGrowth FactorsProstate Growth RegulationProstate Hormone ResponsivenessTransforming Growth Factor Beta ReceptorsTransforming Growth Factor Beta Signaling ModulationTransforming Growth Factor-beta Signaling
LNCaP is an androgen-responsive prostatic cancer cell line that exhibits a bell-shaped growth response to increasing doses of dihydrotestosterone (DHT) in culture.Although the precise mechanism responsible for this growth response to androgen stimulation remains