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MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion

DOIFull Paper Access

51

Citations

36

References

2022

Year

Saravanakumar Marimuthu, Imayavaramban Lakshmanan, Sakthivel Muniyan, Shailendra K. Gautam, Rama Krishna Nimmakayala, Sanchita Rauth, Pranita Atri, Ashu Shah, Namita Bhyravbhatla, Kavita Mallya,
Molecular Cancer Research

Abstract

This study shows that MUC16 plays a critical role in PDAC liver metastasis by mediating NRP2 regulation by JAK2/STAT1 axis, thereby paving the way for future therapy efforts for metastatic PDAC.

References

YearCitations

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