OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment

A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis

Shicheng Su, Qiang Liu, Jingqi Chen et al. · Cancer Cell · 2014 · 785 citations · Full text

Medicine, Cancer Biology, Oncology +17

Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma

Oscar W.H. Yeung, Chung Mau Lo, Chang‐Chun Ling et al. · Journal of Hepatology · 2014 · 493 citations

Medicine, Cancer Biology, Oncology +14

Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in hepatocellular carcinoma

Qingmin Fan, Yingying Jing, Guofeng Yu et al. · Cancer Letters · 2014 · 456 citations

Medicine, Cancer Biology, Oncology +16

Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer

Marco Erreni, Alberto Mantovani, Paola Allavena · Cancer Microenvironment · 2010 · 324 citations · Full text

Medicine, Immunology, Oncology +14

Mammary Morphogenesis and Regeneration Require the Inhibition of EMT at Terminal End Buds by Ovol2 Transcriptional Repressor

Kazuhide Watanabe, Alvaro Villarreal-Ponce, Peng Sun et al. · Developmental Cell · 2014 · 198 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +17