Noninvasive diagnosis of pulmonary hypertension with hyperpolarised¹²⁹Xe magnetic resonance imaging and spectroscopy

Abstract

This study demonstrates the potential to develop ¹²⁹Xe MRI/MRS into a modality with good accuracy in detecting pre- and post-capillary PH. Furthermore, the combination of ¹²⁹Xe dynamic MRS and gas-exchange MRI uniquely provide concurrent, noninvasive assessment of both haemodynamics and gas-exchange impairment that may aid in the detection of PH.