Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomised controlled trial - Concepedia

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Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomised controlled trial

21

Citations

52

References

2022

Year

Ramzi Ajjan, E. Hensor, Francesco Del Galdo, Kave Shams, Afroze Abbas, Lorraine Webber, Lindsay Pegg, Adrian Freeman, Wiebke Arlt, David Russell,

White Rose Research Online (University of Leeds, The University of Sheffield, University of York)

Abstract

Chronic wounds (e.g. diabetic foot ulcers) reduce the quality of life, yet treatments remain limited. Glucocorticoids (activated by the enzyme 11β-hydroxysteroid dehydrogenase type 1, 11β-HSD1) impair wound healing.

References

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