Concepedia

Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combinedwith Olfactory Training to Treat Post-COVID-19 OlfactoryImpairment: A Multi-Center Double-Blinded Randomized Placebo-Controlled Clinical Trial

Arianna Di Stadio, Luca D’Ascanio, Luigi Angelo Vaira, Elena Cantone, Pietro De Luca, Cristina Cingolani, Gaetano Motta, Giacomo De Riu, Federica Vitelli, Giuseppe Spriano,

Current Neuropharmacology · 2022 · 100 citations · 34 references

DOIFull text

Open access

Abstract

Among individuals with olfactory dysfunction post-COVID-19, combining PEA-LUT with olfactory training resulted in greater recovery of smell than olfactory training alone.

References

34

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

Jenny Meinhardt, Josefine Radke, Carsten Dittmayer et al. · Nature Neuroscience · 2020 · 1.5K citations · Full text

, , +14

The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings

Ross W. Paterson, Rachel Brown, Laura Benjamin et al. · Brain · 2020 · 1.1K citations · Full text

COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

Guilherme Dias de Melo, Françoise Lazarini, Sylvain Levallois et al. · Science Translational Medicine · 2021 · 489 citations · Full text

, , +18

Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19

Nelly Kanberg, Nicholas J. Ashton, Lars‐Magnus Andersson et al. · Neurology · 2020 · 384 citations · Full text

Olfactory training is helpful in postinfectious olfactory loss: A randomized, controlled, multicenter study

Michael Damm, Louisa K. Pikart, Heike Reimann et al. · The Laryngoscope · 2013 · 356 citations