Concepedia

Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation

Alexandros A. Polymeris, Fabrice Helfenstein, Pascal Benkert, Stefanie Aeschbacher, David Leppert, Michael Coslovsky, Eline A.J. Willemse, Sabine Schaedelin, Manuel R. Blum, Nicolas Rodondi,

Frontiers in Neuroscience · 2022 · 33 citations · 19 references

DOIFull text

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Abstract

In an elderly AF cohort, both renal function and BMI were associated with sNfL, but only renal function explained a substantial proportion of the sNfL variance. This should be taken into account when using sNfL in elderly patients or patients with cardiovascular disease.

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