Concepedia

Publication | Open Access

Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer’s disease

DOIFull Paper Access

110

Citations

56

References

2022

Year

Leon Smyth, Helen C. Murray, Madison Jean Hill, Eve van Leeuwen, Blake Highet, Nicholas J. Magon, Mahyar Osanlouy, Sophie N. Mathiesen, Bruce G. Mockett, Malvindar K. Singh‐Bains,
Acta Neuropathologica Communications

Abstract

Our report indicates that vascular changes may drive neutrophil adhesion and NETosis, and that neutrophil-derived MPO may lead to vascular oxidative stress and be a relevant therapeutic target in AD.

References

YearCitations

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