Prognostic value of serum/plasma neurofilament light chain for <scp>COVID</scp> ‐19‐associated mortality

Abstract

A substantial increase in serum/plasma NfL reproducibly enhanced COVID-19 mortality prediction. Combined with other prognostic markers, such as ALC and LDH that are routinely measured in ICU patients, NfL measurements might be useful to identify the patients at a high risk of COVID-19-associated mortality, who might still benefit from escalated care.