Phosphoglycerate mutase 5 promotes necroptosis in trophoblast cells through activation of dynamin‐related protein 1 in early‐onset preeclampsia

Abstract

Our results indicate that PGAM5 can promote necroptosis in trophoblast cells through, at least in part, activation of Drp1. It may be used as a new therapeutic target to prevent trophoblast dysfunction in preeclampsia.