Concepedia

miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma

Anup S. Pathania, Philip Prathipati, Omalla A. Olwenyi, Srinivas Chava, Oghenetejiri V. Smith, Subash C. Gupta, Nagendra K. Chaturvedi, Siddappa N. Byrareddy, Donald W. Coulter, Kishore B. Challagundla

Molecular Therapy — Oncolytics · 2022 · 37 citations · 81 references

DOIFull text

Open access

Concepts

Abstract

T and NK cell-mediated anti-tumor responses. These findings demonstrate that miR-15a and miR-15b induce an anti-tumor immune response by targeting PD-L1 in NB.

References

81

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

, , +9

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

, , +17

Cancer Statistics, 2021

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2021 · 17.4K citations · Full text

, , +16

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

Zuguang Gu, Roland Eils, Matthias Schlesner · Bioinformatics · 2016 · 10.9K citations · Full text

, , +16

Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Yi Chen, Lei Wang, Qiuxiang Kang et al. · Cellular Physiology and Biochemistry · 2017 · 10.7K citations · Full text

, , +17