Clinical & Translational Oncology · 2022 · 19 citations · 45 references
MedicineOncologyRadiation OncologyChemotherapyMetastasisMolecular OncologyMalignant NeoplasmsMetastatic Cancer ManagementMetastatic Disease ManagementMetastatic Disease TreatmentNasopharyngeal CancerRadiation TherapyConcurrent Chemoradiation TherapyGemcitabine-based TherapyLocoregional Therapy Response AssessmentMetastatic Disease PalliationMetastatic Disease StagingNasopharyngeal Carcinoma SurgeryPlatinum-based Regimens
Nasopharyngeal carcinoma (NPC) is distinct from other cancers of the head and neck in biology, epidemiology, histology, natural history, and response to treatment. Radiotherapy (RT) is the cornerstone of locoregional treatment of non-disseminated disease and the association of chemotherapy improves the rates of survival. In the case of metastatic disease stages, treatment requires platinum/gemcitabine-based chemotherapy and patients may achieve a long survival time.
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David A. Palma, Robert Olson, Stephen Harrow et al. · The Lancet · 2019 · 1.9K citations
Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma
Yuan Zhang, Lei Chen, Guoqing Hu et al. · New England Journal of Medicine · 2019 · 935 citations · Full text
Medicine, Oncology, Chemotherapy +11