The antiepileptic potential of Vateria indica Linn in experimental animal models: Effect on brain GABA levels and molecular mechanisms

Abstract

Overall, the findings imply that <i>Vateria indica</i> has substantial antiepileptic activities, mediated by positive GABAergic neurotransmission and antioxidant capabilities. To summarize, <i>Vateria indica</i> may provide adequate protection against epileptic seizures, suggesting that it could be used to treat petitmal and grandmal epilepsy. We plan to provide pure lead compounds derived from <i>Vateria indica</i> in the future in order to better understand the role it could play in the development of natural anticonvulsant drugs.