<i>Lactobacillus</i> bloodstream infections genetically related to probiotic use in pediatric hematopoietic cell transplant patients

Abstract

We describe a cluster of 6 pediatric hematopoietic cell transplant recipients with <i>Lactobacillus</i> bacteremia attributed to probiotic use. <i>Lactobacillus</i> isolates cultured from probiotics and patients' blood were proven to be related using whole-genome sequencing. Clinical studies are needed to evaluate the safety of probiotic use in immunocompromised patients.