Unilateral Acute Renal Ischemia-Reperfusion Injury Induces Cardiac Dysfunction through Intracellular Calcium Mishandling

Abstract

Renal I/R injury causes a cardiomyocyte Ca²⁺ cycle dysfunction at medium (contraction-relaxation dysfunction) and long term (Ca²⁺ leak), after 7 and 15 days of renal reperfusion, respectively.