PubMed · 1992 · 17 citations · 0 references
MedicineCardiologyInternal MedicineClinical CardiologyInterventional CardiologyPulmonologyAnticoagulation TherapyMyocardial Infarction ComplicationsPulmonary EmbolismThromboembolic DiseaseThrombolytic TherapyThrombosisDiffuse Pulmonary HemorrhageMonitoring Of Thrombolytic TherapyThrombolysis ComplicationsThrombolysis In Ischemic StrokeThrombolysis-associated Hemorrhage Management
A sixty-years-old man was admitted to the hospital because of acute myocardial infarction of anterior location. He had four episodes of ventricular fibrillation each requiring defibrillation and short-term cardiopulmonary resuscitation (less than 10 minutes). He was then managed with thrombolytic therapy, therapeutic doses of heparin and aspirin. He had persistent haemoptysis, chest X-ray revealing a diffuse bilateral alveolar infiltration. There was a continuous decrease in hemoglobin and hematocrit levels, with an evident clinical-radiographic dissociation. Right cardiac catheterisation showed a normal left ventricular function. The single breath carbon monoxide diffusing capacity (DLCOsb) was high, indicative of a diffuse intrapulmonary haemorrhage causing the alveolar infiltration.