Updated international consensus report on the investigation and management of primary immune thrombocytopenia

TLDR

Immune thrombocytopenia treatment has evolved significantly over the past decade. The article updates the 2010 International Consensus Report on ITP. The authors performed a systematic review of 2009–2018 literature and had an expert panel evaluate and grade studies to develop updated recommendations. The updated consensus offers guidance on diagnosing and treating ITP across adults, pregnant patients, and children, including quality‑of‑life considerations.

Abstract

Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia (ITP). This article is an update of the International Consensus Report published in 2010. A critical review was performed to identify all relevant articles published between 2009 and 2018. An expert panel screened, reviewed, and graded the studies and formulated the updated consensus recommendations based on the new data. The final document provides consensus recommendations on the diagnosis and management of ITP in adults, during pregnancy, and in children, as well as quality-of-life considerations.