Common variant p.<scp>D</scp>19<scp>H</scp> of the hepatobiliary sterol transporter <scp><i>ABCG8</i></scp> increases the risk of gallstones in children

Abstract

The p.D19H ABCG8 and, to a lesser extent, NPC1L1 rs217434 variants increase the risk of early-onset gallstone formation. These results point to the presence of a common lithogenic pathway in children and adults.