A simple synthetic entryway into new families of NHC–gold-amido complexes and their <i>in vitro</i> antitumor activity

Ekaterina A. Martynova, Thomas Scattolin, Enrico Cavarzerani, Min Peng, Kristof Van Hecke, Flavio Rizzolio, Steven P. Nolan

Dalton Transactions · 2022 · 16 citations · 23 references

Concepts

Abstract

anticancer activity of these gold-complexes was investigated on three human cancer cell lines. A number of these show comparable or even better antiproliferative activity than cisplatin. Noteworthy is the non-toxicity of most of the complexes on normal cells.

References

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