Dalton Transactions · 2022 · 16 citations · 23 references
PharmacyMedicinal ChemistryPharmacologyCancer PharmacologyDrug DiscoverySynthetic Medicinal ChemistryCancer NanomedicineCytotoxic ChemotherapyLigand BindingLigand-based DesignAnticancer ActivityAnticancer ChemotherapyAnticancer Natural ProductsChemical Synthesis Of AnaloguesDrug-ligand ComplexationMild Reaction ConditionsOrganometallic Anticancer AgentsPlatinum Compounds
anticancer activity of these gold-complexes was investigated on three human cancer cell lines. A number of these show comparable or even better antiproliferative activity than cisplatin. Noteworthy is the non-toxicity of most of the complexes on normal cells.
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An overview of N-heterocyclic carbenes
Matthew N. Hopkinson, Christian Richter, Michael Schedler et al. · Nature · 2014 · 4.2K citations