The Role of Histogram-Based Textural Analysis of <sup>18</sup>F-FDG PET/CT in Evaluating Tumor Heterogeneity and Predicting the Prognosis of Invasive Lung Adenocarcinoma

Abstract

HBTFs were tightly associated with clinicopathological factors causing TH. Among the ¹⁸F-FDG PET/CT parameters, only skewness and kurtosis were associated with lymph node involvement, whereas SUV_max was the only independent predictor of OS. TH measurement with HBTFs may contribute to conventional metabolic parameters in guiding precision medicine for ILA.