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Single-cell transcriptomics reveals a low CD8<sup>+</sup> T cell infiltrating state mediated by fibroblasts in recurrent renal cell carcinoma

68

Citations

38

References

2022

Year

Abstract

We delineated the heterogeneity of reRCC and highlighted an innovative mechanism that CAFs acted as a suppressor of CD8<sup>+</sup> T cells via Gal1. Targeting Gal1 combined with anti-PD1 showed promising efficacy in treating RCC.

References

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