Specific IgE and IgG4 Profiles of House Dust Mite Components in Allergen-Specific Immunotherapy

Abstract

AIT can induce the production of sIgG4 to HDM components. However, the increased sIgG4 levels of HDM component do not correlate with the corresponding sIgE levels at baseline or with AIT response. sIgG4 to HDM components do not qualify as a biomarker to evaluate the efficacy of AIT.