Molecular engineering of complexation between RNA and biodegradable cationic gemini surfactants: role of the hydrophobic chain length

Abstract

The effects of the hydrophobic alkyl chain length of C m -E2O-C m gemini surfactants ( m = 12, 14 and 16) on ribonucleic acid were investigated using different methods. The various calculated parameters revealed that complexation occurs via an intercalative binding mode.