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Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo

Bioorganic ChemistryAntimicrobial SusceptibilityAntibioticsNatural SciencesMolecular BiologyAntibacterial AgentPotent Antimicrobial/antibiofilm ActivityMicrobiologyAntimicrobial ChemotherapyAntimicrobial CompoundMedicineAntimicrobial ResistanceFascaplysin DerivativesDrug Resistance