Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model - Concepedia

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Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model

DOI Full Paper Access

13

Citations

50

References

2022

Year

Carlos Minoru Omura, Daniela Dero Lüdtke, Verônica Vargas Horewicz, Paula Franson Fernandes, Taynah de Oliveira Galassi, Afonso Shiguemi Inoue Salgado, Juliete Palandi, Heloiza dos Santos Baldança, Edsel B. Bittencourt, Josiel Mileno Mack,

Frontiers in Physiology

Abstract

Taken together, the results confirm the anti-hyperalgesic effect of AJM and suggest a central neuroimmunomodulatory effect in a model of persistent inflammation targeting the pro-inflammatory cytokines IL-1β and TNF.

References

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