ACS Catalysis · 2022 · 27 citations · 67 references
Natural SciencesChemical EngineeringChemistryCatalysisOrganic ChemistryOrganometallic ChemistryHeterocyclic ChemistryPhotocatalysisPhotochemical SynthesisPhotochemistryRadical ReactionsReaction MechanismsC - H Bond FunctionalizationChemical ReductantsHeterocycle FunctionalizationKetone FunctionalizationMetal CatalystsPhotochemical FunctionalizationTransition Metal CatalystsTriplet State Photochemistry
A general strategy for enabling a light-induced defunctionalization of sp3 C–heteroatom and sp3 C–C bonds with triplet ketone catalysts and bipyridine additives is disclosed. This protocol is characterized by its broad scope without recourse to transition metal catalysts or stoichiometric exogeneous reductants, thus offering a complementary technique for activating σ sp3 C–C(heteroatom) bonds. Preliminary mechanistic studies suggest that the presence of 2,2′-bipyridines improves the lifetime of ketyl radical intermediates.
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Reduction of aryl halides by consecutive visible light-induced electron transfer processes
Indrajit Ghosh, Tamal Kanti Ghosh, Javier I. Bardagí et al. · Science · 2014 · 1.2K citations · Full text