Organic Chemistry Frontiers · 2022 · 42 citations · 154 references
Natural SciencesChemistryMedicinal ChemistryCatalysisOrganic ChemistrySynthetic Medicinal ChemistryCatalytic MechanismsHeterocycle SynthesisOrganic SynthesisReaction MechanismsTransition Metal ChemistryTransition Metal ComplexesC - H Bond FunctionalizationC-h ActivationC-h Bond ActivationDirected C - H ActivationHeterocycle FunctionalizationTransition Metal-catalyzed SynthesisTransition-metal-catalyzed FunctionalizationTransition-metal-catalyzed Heterocycle Synthesis
This review focuses on the advances in transition-metal catalyzed reactions with fluorinated building blocks via directed C–H bond activation for the construction of diverse organic molecules with an insight into the probable mechanistic pathway.
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The Many Roles for Fluorine in Medicinal Chemistry
William K. Hagmann · Journal of Medicinal Chemistry · 2008 · 3.6K citations · Full text