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Liraglutide Activates Type 2 Deiodinase and Enhances β3-Adrenergic-Induced Thermogenesis in Mouse Adipose Tissue

DOIFull Paper Access

29

Citations

40

References

2022

Year

Fernanda Cerqueira Barroso Oliveira, Eduarda Jacinto Bauer, Carolina Martins Ribeiro, Sidney Alcântara Pereira, Bruna Teles Soares Beserra, Simone Magagnin Wajner, Ana Luiza Maia, Francisco de Assis Rocha Neves, Michella Soares Coêlho, Angélica Amorim Amato
Frontiers in Endocrinology

Abstract

Liraglutide exhibits additive effects to those of β3-adrenergic stimulation in thermogenic fat and increases D2 activity in BAT, implying that it may activate this adipose tissue depot by increasing intracellular thyroid activation, adding to the currently known mechanisms of GLP-1A-induced weight loss.

References

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