Science Advances · 2022 · 35 citations · 51 references
MedicineGeneticsMolecular GeneticsCytogeneticsRecombinationCrossover FormationMeiotic RecombinationRecombination InitiationRecombination IntermediatesRecombination ProteinsRecombination RegulationMeiotic Recombination ControlMeiotic Recombination IntermediatesMeiotic Recombination PathwaysMeiotic Recombination ProteinsRad51 Protein
mutant mice results from compromised DSB repair in PARs due to destabilization of recombination intermediates rather than defects in DSB generation or synapsis. Our findings provide direct experimental evidence that XY recombination may use a PAR-specific DSB repair mechanism mediated by factors that are not essential for recombination on autosomes.
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An atypical topoisomerase II from archaea with implications for meiotic recombination
Agnès Bergerat, Bernard de Massy, Danielle Gadelle et al. · Nature · 1997 · 943 citations
Chromosome Synapsis Defects and Sexually Dimorphic Meiotic Progression in Mice Lacking Spo11
Frédéric Baudat, Katia Manova, Julie Pui Yuen et al. · Molecular Cell · 2000 · 729 citations · Full text
Life Sciences, Biology, Genetics +16