Asymmetric hydroamination with far fewer chiral species than copper centers achieved by tuning the structure of supramolecular helical catalysts

Abstract

Mixing a BTA ligand (in black), a “sergeant” (in blue) and an achiral BTA additive (in orange) affords the amination product in 75% e.e. even though only one “sergeant” for ca. 10 copper centers are present in the supramolecular helical catalyst.