Effectiveness of rosuvastatin plus colchicine, emtricitabine/tenofovir and combinations thereof in hospitalized patients with COVID-19: a pragmatic, open-label randomized trial

Hernando Gaitán‐Duarte, Carlos Álvarez, Carlos Rincón, Nancy Yomayusa-González, Jorge Alberto Cortés, Juan Carlos Villar, Juan Sebastián Bravo-Ojeda, Ángel A. García-Peña, Wilson Adarme Jaimes, Viviana Rodríguez,

EClinicalMedicine · 2021 · 35 citations · 26 references

DOIFull text

Open access

Abstract

The combined use of FTC/TDF+COLCH+ROSU reduces the risk of 28-day mortality and the need for invasive mechanical ventilation in hospitalized patients with pulmonary compromise from COVID-19. More randomized controlled trials are needed to compare the effectiveness and cost of treatment with this combination versus other drugs that have been shown to reduce mortality from SARS-CoV-2 infection and its usefulness in patients with chronic statin use.

References

26