Nanoengineered therapy aiming at the etiology of rheumatoid arthritis

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

Josef S Smolen, Robert Landewé, J. W. J. Bijlsma et al. · Annals of the Rheumatic Diseases · 2020 · 2.8K citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +15

Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Elizabeth A. Leadbetter, Ian R. Rifkin, Andreas M. Hohlbaum et al. · Nature · 2002 · 1.9K citations

Life Sciences, Immunology, Molecular Biology +14

Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

Jane Tian, Ana M. Avalos, Su-Yau Mao et al. · Nature Immunology · 2007 · 1.4K citations

Life Sciences, Immunology, Molecular Biology +12

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

Ritika Khandpur, Carmelo Carmona‐Rivera, Anuradha Vivekanandan‐Giri et al. · Science Translational Medicine · 2013 · 1.3K citations

Life Sciences, Immunology, Molecular Biology +13

Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins

Alex J. MacGregor, Harold Snieder, Alan S. Rigby et al. · Arthritis & Rheumatism · 2000 · 1.2K citations

Life Sciences, Clinical Sciences, Genetics +17