The mTORC1‐eIF4F axis controls paused pluripotency

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

Huafeng Zhang, Marta Bosch‐Marcé, Larissa A. Shimoda et al. · Journal of Biological Chemistry · 2008 · 1.6K citations · Full text

A unifying model for mTORC1-mediated regulation of mRNA translation

Carson C. Thoreen, Lynne Chantranupong, Heather R. Keys et al. · Nature · 2012 · 1.5K citations · Full text

Systems Biology, Signal Transduction, Molecular Regulation +5

Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

David A. Guertin, Deanna M. Stevens, Carson C. Thoreen et al. · Developmental Cell · 2006 · 1.4K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +8

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Andrew C. Hsieh, Yi Liu, Merritt P. Edlind et al. · Nature · 2012 · 1.3K citations · Full text

Tumor Biology, Signal Transduction, Signaling Pathway +10

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

Anne‐Claude Gingras, Steven P. Gygi, Brian Raught et al. · Genes & Development · 1999 · 1.3K citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +15