Concepedia

A randomized clinical trial evaluating the effect of empagliflozin on triglycerides in obese adults: Role of visceral fat

Min Hee Lee, Ian J. Neeland, Natalia de Albuquerque Rocha, Connor Hughes, Craig R. Malloy, Eunsook S. Jin

Metabolism Open · 2021 · 11 citations · 27 references

DOIFull text

Open access

Abstract

The effect of empagliflozin on triglycerides in obese adults differed depending on VAT. Empagliflozin suppressed triglyceride synthesis in the subjects with low VAT, but tended to increase triglycerides in those with high VAT.

References

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Ele Ferrannini, Elza Muscelli, Silvia Frascerra et al. · Journal of Clinical Investigation · 2014 · 1.1K citations · Full text

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Norbert Stefan · Archives of Internal Medicine · 2008 · 1K citations

Intra-Abdominal Fat Is a Major Determinant of the National Cholesterol Education Program Adult Treatment Panel III Criteria for the Metabolic Syndrome

Darcy B. Carr, Kristina M. Utzschneider, Rebecca L. Hull et al. · Diabetes · 2004 · 988 citations · Full text

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Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

Elisa Fabbrini, Faidon Magkos, B. Selma Mohammed et al. · Proceedings of the National Academy of Sciences · 2009 · 961 citations · Full text

Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production

Aurora Merovci, Carolina Solis‐Herrera, Giuseppe Daniele et al. · Journal of Clinical Investigation · 2014 · 769 citations · Full text

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