Concepedia

Publication | Open Access

Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: a translational study

DOIFull Paper Access

40

Citations

20

References

2021

Year

Marina Cerrone, Grecia M. Marrón-Liñares, Chantal J.M. van Opbergen, Sarah Costa, Mimount Bourfiss, Marta Pérez-Hernández, Florencia Schlamp, Fabián Sanchis‐Gomar, Kabir Malkani, Kamelia Drenkova,
European Heart Journal

Abstract

We speculate that exercise challenges a cardiomyocyte "desmosomal reserve" which, if impaired genetically (e.g., PKP2 loss), accelerates progression of cardiomyopathy.

References

YearCitations

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