p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms

Abstract

p53 IHC patterns may be used as predictors of <i>TP53</i> gene mutations and therefore could be potential surrogate markers for <i>TP53</i> mutations in GI-NENs and could distinguish between well-differentiated NETs and poorly differentiated NECs.