Concepedia

Antisense Oligonucleotide In Vitro Protein Binding Determination in Plasma, Brain, and Cerebral Spinal Fluid Using Hybridization LC-MS/MS

Guilherme J. Guimaraes, Long Yuan, Pei Li

Drug Metabolism and Disposition · 2021 · 25 citations · 28 references

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References

28

Targeting Huntingtin Expression in Patients with Huntington’s Disease

New England Journal of Medicine · 2019 · 670 citations · Full text

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An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

Timothy M. Miller, Alan Pestronk, William David et al. · The Lancet Neurology · 2013 · 607 citations · Full text

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Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development

HM Jones, K Rowland‐Yeo · CPT Pharmacometrics & Systems Pharmacology · 2013 · 582 citations · Full text

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Prediction of Pharmacokinetics Prior to In Vivo Studies. 1. Mechanism‐Based Prediction of Volume of Distribution

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2002 · 560 citations

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Antisense oligonucleotide therapy for neurodegenerative disease

Richard Smith · Journal of Clinical Investigation · 2006 · 505 citations · Full text

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