Internal Medicine · 2021 · 18 citations · 34 references
MedicineImmunologyInternal MedicineAutoimmunityImmunopathologyRheumatologyAutoimmune DiseasesAutoimmune Rheumatic DiseasesInflammatory ArthritisRheumatoid ArthritisVaccinationBicipital TenosynovitisBilateral Pain PatternsDifferential Diagnosis CriteriaDifferential Symptom DiagnosisPolymyalgia RheumaticaPrednisolone UseSubacromial BursitisTenosynovitis Imaging
We herein report the case of an 80-year-old Japanese woman who presented to our hospital with bilateral pain in the shoulders and hips lasting for a month since 2 days after the second dose of the BNT162b2 COVID-19 vaccine. Her physical findings, laboratory data, and ultrasonographic findings of bilateral biceps tenosynovitis and lateral subacromial bursitis were consistent with a diagnosis of polymyalgia rheumatica (PMR). She was successfully treated with oral prednisolone 15 mg/day. Although a causal relationship could not be definitively confirmed, PMR should be considered as a differential diagnosis in cases of persistent myalgia after administration of the BNT162b2 vaccine.
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Systems vaccinology of the BNT162b2 mRNA vaccine in humans
Prabhu S. Arunachalam, Madeleine Scott, Thomas Hagan et al. · Nature · 2021 · 575 citations · Full text
Bhaskar Dasgupta, Marco A. Cimmino, Hilal Maradit Kremers et al. · Arthritis & Rheumatism · 2012 · 406 citations · Full text